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Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and disease

5 Sept 2024

Abstract excerpt

Kidney injury disrupts the intricate renal architecture and triggers limited regeneration, together with injury-invoked inflammation and fibrosis. Deciphering the molecular pathways and cellular interactions driving these processes is challenging due to the complex tissue structure. Here, we apply single cell spatial transcriptomics to examine ischemia-reperfusion injury in the mouse kidney. Spatial...

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PMID: 39237549
DOI: 10.1038/s41467-024-51186-z

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