Shared multicellular injury programs of acute and chronic kidney disease enable mechanistic patient stratification

Abstract excerpt

Acute kidney injury (AKI) and chronic kidney disease (CKD) are two interconnected clinical conditions, both defined by degree of functional impairment, but with heterogeneous clinical trajectories. Using new transcriptomic technologies, recent studies have described the cellular diversity in the healthy and injured kidney at the single cell level. Here, we used single nucleus transcriptomics to investigate the mol...

Topics

Open a Topic to create a Post that cites this publication.

• Acute Kidney Injury Research
• Chronic Kidney Disease and Diabetes
• Dialysis and Renal Disease Management
• Renal and related cancers
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

f72cce7f-867e-588a-8472-769d1946cf28

DOI

10.64898/2026.03.05.26347522