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Article

Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model

1 Dec 2021

Abstract excerpt

BACKGROUND: Single-cell sequencing technologies have advanced our understanding of kidney biology and disease, but the loss of spatial information in these datasets hinders our interpretation of intercellular communication networks and regional gene expression patterns. New spatial transcriptomic sequencing platforms make it possible to measure the topography of gene expression at genome depth. METHODS: We...

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PMID: 34853151
DOI: 10.1681/asn.2021081150

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