Article
Age-dependent association between butyrylcholinesterase K-variant and Alzheimer disease-related neuropathology in human brains.
Neuroscience letters - 1 Mar 2002
Ghebremedhin Estifanos, Thal Dietmar R, Schultz Christian, Braak Heiko
Abstract excerpt
The association between the K-variant of the butyrylcholinesterase gene (BCHE-K) and Alzheimer disease (AD) or AD-related neuropathology has been reported to date with conflicting results. Here, we determined in a sample of 521 cases the severity of AD-related neuropathology and the polymorphisms of both BCHE-K and apolipoprotein E (ApoE). Histopathologically, all brains were classified according to procedures...
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