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Article

Influence of Butyrylcholinesterase in Progression of Mild Cognitive Impairment to Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Gabriel António José, Almeida Maria Rosário, Ribeiro Maria Helena, Carneiro Diogo, Valério Daniela, Pinheiro Ana Cristina, Pascoal Rui, Santana Isabel, Baldeiras Inês

Abstract excerpt

BACKGROUND: Several demographic and genetic prognostic factors of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) have been recognized so far. The most frequent polymorphism of butyrylcholinesterase (BuChE), the K-variant, has been proposed as a risk factor for AD, but data regarding its influence on early disease progression is still limited. OBJECTIVE: To investigate the influence of...

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PMID: 29254094
DOI: 10.3233/JAD-170695

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