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Harnessing CRISPR-Cas9 for genome editing in <i>Streptococcus pneumoniae</i>

2020-06-13

Abstract excerpt

CRISPR systems provide bacteria and archaea with adaptive immunity against viruses and plasmids by detection and cleavage of invading foreign DNA. Modified versions of this system can be exploited as a biotechnological tool for precise genome editing at a targeted locus. Here, we developed a novel, replicative plasmid that carries the CRISPR-Cas9 system for RNA-programmable, genome editing by counterselection in t...

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Identifiers and source

Literature Corpus work
6c623ada-d86b-5eb6-8297-31745ee1b712
DOI
10.1101/2020.06.13.149682
Open publication

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Harnessing CRISPR-Cas9 for genome editing in <i>Streptococcus pneumoniae</i>DOI 10.1101/2020.06.13.149682
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