Article

Defect in hematopoiesis and embryonic lethality at midgestation of <i>Vps13a/Vps13c</i> double knockout mice

2025-05-13

Abstract excerpt

<h4>ABSTRACT</h4> VPS13 is the founding member of a family of proteins that mediate lipid transfer at intracellular membrane contact sites by a bridge-like mechanism. Mammalian genomes comprise 4 VPS13 genes encoding proteins with distinct localizations and function. The gene duplication resulting in VPS13A and VPS13C is the most recent in evolution and, accordingly, these two proteins are the most similar to...

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Literature Corpus work: 6c61aebc-15e9-5890-9d5b-2314cc79bffe
DOI: 10.1101/2025.05.09.653147

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