Article
Yeast and other lower eukaryotic organisms for studies of Vps13 proteins in health and disease.
Traffic (Copenhagen, Denmark) - 1 Nov 2017
Rzepnikowska Weronika, Flis Krzysztof, Muñoz-Braceras Sandra, Menezes Regina, Escalante Ricardo, Zoladek Teresa
Abstract excerpt
Human Vps13 proteins are associated with several diseases, including the neurodegenerative disorder Chorea-acanthocytosis (ChAc), yet the biology of these proteins is still poorly understood. Studies in Saccharomyces cerevisiae, Dictyostelium discoideum, Tetrahymena thermophila and Drosophila melanogaster point to the involvement of Vps13 in cytoskeleton organization, vesicular trafficking, autophagy,...
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