Article

VPS13A and VPS13C influence lipid droplet abundance

2022-06-23

Abstract excerpt

<h4>ABSTRACT</h4> Lipid transfer proteins mediate the exchange of lipids between closely apposed membranes at organelle contact sites and play key roles in lipid metabolism, membrane homeostasis, and cellular signaling. A recently discovered novel family of lipid transfer proteins, which includes the VPS13 proteins (VPS13A-D), adopt a rod-like bridge conformation with an extended hydrophobic groove that enables t...

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Literature Corpus work: 68643c51-e335-53d8-88e3-8bdcb308a0a7
DOI: 10.1101/2022.06.21.497109

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