Article

A single cell framework for multi-omic analysis of disease identifies malignant regulatory signatures in mixed phenotype acute leukemia

2019-07-09

Abstract excerpt

In order to identify the molecular determinants of human diseases, such as cancer, that arise from a diverse range of tissue, it is necessary to accurately distinguish normal and pathogenic cellular programs. 1–3 Here we present a novel approach for single-cell multi-omic deconvolution of healthy and pathological molecular signatures within phenotypically heterogeneous malignant cells. By first creating immunophe...

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Literature Corpus work: 6c325800-42eb-5ece-aef3-d692e19bc181
DOI: 10.1101/696328

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