Article
The genomic and biological complexity of mixed phenotype acute leukemia.
Critical reviews in clinical laboratory sciences - 1 May 2021
Andrews Claire, Tierens Anne, Minden Mark
Abstract excerpt
Mixed phenotype acute leukemia (MPAL) is a heterogeneous group of leukemias that are defined immunophenotypically by antigen expression on blasts of both myeloid and lymphoid lineage. With the exception of BCR-ABL positive and KMT2A rearranged MPAL, the biology of the majority of MPAL remains uncertain. Several recent studies have explored the genomic and epigenetic landscape of MPAL and have suggested a further...
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