Article

Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data

2020-10-23

Abstract excerpt

Revealing the gene targets of distal regulatory elements is challenging yet critical for interpreting regulome data. Experiment-derived enhancer-gene links are restricted to a small set of enhancers and/or cell types, while the accuracy of genome-wide approaches remains elusive due to the lack of a systematic evaluation. We combined multiple spatial and in silico approaches for defining enhancer locations and lin...

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Literature Corpus work: feac9546-8b0b-5b96-b650-4b8561750311
DOI: 10.1101/2020.10.22.351049

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