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T-bet expressing Tr1 cells driven by dietary signals dominate the small intestinal immune landscape

2025-07-04

Abstract excerpt

Intestinal immunity defends against enteric pathogens, mediates symbiotic relationships with the resident microbiota, and provides tolerance to food antigens, safeguarding critical nutrient absorption and barrier functions of this mucosal tissue. Despite the abundance of tissue resident activated T cells, their contributions to these various roles remains poorly understood. Here, we identify a dominant population...

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Literature Corpus work
8c95464f-487a-568e-86ad-a7772442fb57
DOI
10.1101/2025.06.30.662190
Open publication

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T-bet expressing Tr1 cells driven by dietary signals dominate the small intestinal immune landscapeDOI 10.1101/2025.06.30.662190
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