Tissue-specific antigen-presenting cells contribute to distinct phenotypes of allergy.

Abstract excerpt

Antigen-presenting cells (APCs) are critical cells bridging innate and adaptive immune responses by taking up, processing, and presenting antigens to naïve T cells. At steady state, APCs thus control both tissue homeostasis and the induction of tolerance. In allergies however, APCs drive a Th2-biased immune response that is directed against otherwise harmless antigens from the environment. The main types of APCs...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Allergens
• Share to Antigen-Presenting Cells
• Share to Hypersensitivity