Article

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

2022-09-27

Abstract excerpt

Interactions with commensal microbes shape host immunity on multiple levels and are recognized to play a pivotal role in human health and disease. In this study, we show that MHC-II restricted, commensal-reactive T cells in the colon of both humans and mice acquire transcriptional and functional characteristics typically associated with innate-like T cells, including the expression of the key transcription factor...

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Identifiers and source

Literature Corpus work: 1f909283-336f-52d5-8b45-31c843d6ce3a
DOI: 10.1101/2022.09.26.509581

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