Article

Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues

2024-05-10

Abstract excerpt

Conventional dendritic cells (cDCs) are potent antigen presenting cells (APCs) that exhibit tissue and age-specific diversity allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in vaccination and cancer. Here, we resolve conflicting data about expression of retinoic acid receptor-related orphan receptor-γt (RORψt) in cDCs. We show that RORψt + DCs exist in m...

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Literature Corpus work: 6a48b805-5587-50fe-9037-fa6c25130de1
DOI: 10.1101/2024.05.06.592772

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