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G1-Cyclin2 (Cln2) promotes chromosome hypercondensation in <i>eco1/ctf7 rad61</i> null cells during hyperthermic stress in <i>Saccharomyces cerevisiae</i>

2022-05-29

Abstract excerpt

<h4>ABSTRACT</h4> Eco1/Ctf7 is a highly conserved acetyltransferase that activates cohesin complexes and is critical for sister chromatid cohesion, chromosome condensation, DNA damage repair, nucleolar integrity, and gene transcription. Mutations in the human homolog of ECO1 ( ESCO2/EFO2 ), or in genes that encode cohesin subunits, result in severe developmental abnormalities and intellectual disabilities refer...

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Literature Corpus work
6b453a37-698c-52f0-b826-700d84ed6ef3
DOI
10.1101/2022.05.27.493609
Open publication

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G1-Cyclin2 (Cln2) promotes chromosome hypercondensation in <i>eco1/ctf7 rad61</i> null cells during hyperthermic stress in <i>Saccharomyces cerevisiae</i>DOI 10.1101/2022.05.27.493609
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