Article

Polyol sugar osmolyte - sorbitol corrects chromosome cohesion and translational defects in cohesin mutants

2024-09-05

Abstract excerpt

The cohesin protein complex plays a very important role in chromosome segregation, transcription, DNA replication and chromosome condensation. Mutations in cohesin proteins give rise to a disease collectively referred to as Cohesinopathies. The major cause of Cohesinopathies arise due to defects associated with gene expression, that give rise to developmental disorders. In this study, we have used Saccharomyces c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a7521e7b-af64-56af-ba88-7e9ed6023512
DOI: 10.1101/2024.09.04.610945

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Polyol sugar osmolyte - sorbitol corrects chromosome cohesion and translational defects in cohesin mutantsDOI 10.1101/2024.09.04.610945Read

G1-Cyclin2 (Cln2) promotes chromosome hypercondensation in <i>eco1/ctf7 rad61</i> null cells during hyperthermic stress in <i>Saccharomyces cerevisiae</i>Semantic proximity Read

Translational mechanisms at work in the cohesinopathies.Semantic proximity Read

Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae.Semantic proximity Read

The acetyltransferase Eco1 elicits cohesin dimerization during S phaseSemantic proximity Read

The defects in cell wall integrity and G2-M transition of the ∆htl1 mutant are interconnected.Semantic proximity Read

Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water.Semantic proximity Read

Heavy ion beam irradiation-induced mutational profiles in Saccharomyces cerevisiae and their dependencies on dose and intracellular state inform an enhanced microbial breeding strategy.Semantic proximity Read

A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.Semantic proximity Read

Defects in Protein Folding Machinery Affect Cell Wall Integrity and Reduce Ethanol Tolerance in S. cerevisiae.Semantic proximity Read

Fdo1, Fkh1, Fkh2 and the Swi6-Mbp1 MBF complex regulate Mcd1 levels to impact eco1 rad61 cell growth in Saccharomyces cerevisiaeSemantic proximity Read

The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage.Semantic proximity Read

Genetic analysis of desiccation tolerance in Sachharomyces cerevisiae.Semantic proximity Read