Article

The power of pathway-based polygenic risk scores

2021-06-28

Abstract excerpt

<title>Abstract</title> <p>Polygenic risk scores (PRSs) have been among the leading advances in biomedicine in recent years. As a proxy of genetic liability, PRSs are utilised across multiple fields and applications. While numerous statistical and machine learning methods have been developed to optimise their predictive accuracy, all of these distil genetic liability to a single number based on aggregation of an...

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Literature Corpus work: 6b42775f-c13c-51b5-bb3d-5ccbd9fb1f7d
DOI: 10.21203/rs.3.rs-643696/v1

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