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NovAT tool-Reliable novel HLA alleles identification from next-generation sequencing data.

HLA - 1 Jan 2022

Simakova Tamara, Suvorova Arina, Krivonosova Kristina, Abramova Anna, Loginova Maria, Paramonov Igor

Abstract excerpt

HLA molecules are expressed in almost all nucleated cells of the body. These molecules are extremely variable and responsible for tissue specificity recognition. Precise HLA typing is crucial for tissue and organ transplantation. Usually, HLA-typing NGS methods are based on the assignment of reads to a certain previously reported HLA allele presented in the IPD-IMGT/HLA Database. But there is a limited number of...

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PMID: 34791827
DOI: 10.1111/tan.14491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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