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A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Hundreds of human genes are associated with neurological diseases, but translation into tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to investigate genetic contributions to neurological diseases. However, current CRISPR-Cas9 methods are difficult to apply to large genetic screens studying behavioural phenotypes. To facilitate rapid genetic screening, we de...

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Literature Corpus work
cb6297e1-c9b2-5a1d-985e-3f8abddcbea8
DOI
10.1101/2020.06.04.133462
Open publication

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A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypesDOI 10.1101/2020.06.04.133462
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