Article

Predicting MHC-I ligands across alleles and species: How far can we go?

2024-05-10

Abstract excerpt

<h4>ABSTRACT</h4> CD8 + T-cell activation is initiated by the recognition of epitopes presented on class I major histocompatibility complex (MHC-I) molecules. Identifying such epitopes is useful for molecular understanding of cellular immune responses and can guide the development of personalized vaccines for various diseases including cancer. Here, we capitalize on high-quality MHC-I peptidomics data available...

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Literature Corpus work: 6a89e39a-b266-5f44-a963-b93b01fd1440
DOI: 10.1101/2024.05.08.593183

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