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MHCflurry 2.0: Improved Pan-Allele Prediction of MHC Class I-Presented Peptides by Incorporating Antigen Processing.

Cell systems - 22 Jul 2020

O'Donnell Timothy J, Rubinsteyn Alex, Laserson Uri

Abstract excerpt

Computational prediction of the peptides presented on major histocompatibility complex (MHC) class I proteins is an important tool for studying T cell immunity. The data available to develop such predictors have expanded with the use of mass spectrometry to identify naturally presented MHC ligands. In addition to elucidating binding motifs, the identified ligands also reflect the antigen processing steps that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32711842
DOI: 10.1016/j.cels.2020.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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