Article

AI-MHC: an allele-integrated deep learning framework for improving Class I & Class II HLA-binding predictions

2018-05-25

Abstract excerpt

<h4>Motivation</h4> The immune system has potential to present a wide variety of peptides to itself as a means of surveillance for pathogenic invaders. This means of surveillances allows the immune system to detect peptides derives from bacterial, viral, and even oncologic sources. However, given the breadth of the epitope repertoire, in order to study immune responses to these epitopes, investigators have relied...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e39962fe-f03a-5972-942b-1a84615e9d33
DOI: 10.1101/318881

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

AI-MHC: an allele-integrated deep learning framework for improving Class I & Class II HLA-binding predictionsDOI 10.1101/318881Read

MHCAttnNet: predicting MHC-peptide bindings for MHC alleles classes I and II using an attention-based deep neural model.Semantic proximity Read

HLA class I binding prediction via convolutional neural networksSemantic proximity Read

Deep learning pan-specific model for interpretable MHC-I peptide binding prediction with improved attention mechanism.Semantic proximity Read

OnionMHC: A Deep Learning Model for Peptide - HLA-A*02:01 Binding Predictions using both Structure and Sequence Feature SetsSemantic proximity Read

Connecting MHC-I-binding motifs with HLA alleles via deep learning.Semantic proximity Read

MHCBind: A Pan- and Allele-Specific Model for Predicting Class I MHC-Peptide Binding AffinitySemantic proximity Read

TransHLA: A Hybrid Transformer Model for HLA-Presented Epitope DetectionSemantic proximity Read

Deep convolutional neural networks for pan-specific peptide-MHC class I binding prediction.Semantic proximity Read

Structure modeling and specificity of peptide-MHC class I interactions using geometric deep learningSemantic proximity Read

Attention mechanism-based deep learning pan-specific model for interpretable MHC-I peptide binding predictionSemantic proximity Read

HLAIIPred: Cross-Attention Mechanism for Modeling the Interaction of HLA Class II Molecules with PeptidesSemantic proximity Read

NetTCR: sequence-based prediction of TCR binding to peptide-MHC complexes using convolutional neural networksSemantic proximity Read