Article
How to Predict Binding Specificity and Ligands for New MHC-II Alleles with MixMHC2pred.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024
Racle Julien, Gfeller David
Abstract excerpt
MHC-II molecules are key mediators of antigen presentation in vertebrate species and bind to their ligands with high specificity. The very high polymorphism of MHC-II genes within species and the fast-evolving nature of these genes across species has resulted in tens of thousands of different alleles, with hundreds of new alleles being discovered yearly through large sequencing projects in different species. Here...
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