Transcriptional Analysis Reveals Alteration of Lung Macrophages Following Mesenchymal Stem Cell Therapy in Neonatal Mice With Hyperoxia-Induced Injury

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Lung immaturity is one of the most serious consequences of growth restriction and premature birth. Preterm babies often require mechanical ventilation to survive, but exposure to high levels of oxygen can permanently damage the lungs and interrupts normal development. As lung macrophages play an important role in hyperoxic lung injury and repair, our objective wa...

Topics

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• Bronchopulmonary Dysplasia
• Congenital Diaphragmatic Hernia Studies
• Genotype
• Hyperoxia
• Lung
• Mice
• Neonatal Respiratory Health Research
• Sequence Analysis, RNA

Identifiers and source

Literature Corpus work

6a7e7d6a-aaf4-546f-bce7-bcdfecdfdb6c

DOI

10.21203/rs.3.rs-72222/v1