Article
High-mobility group box1 peptide ameliorates bronchopulmonary dysplasia via suppressing inflammation and fibrosis in a mouse model
2021-09-15
Abstract excerpt
Bronchopulmonary dysplasia (BPD) is a chronic lung disorder that affect approximately 40% of preterm infants, with no established curative therapy. The administration of mesenchymal stem cells (MSCs) to BPD patients has shown promising outcomes. Previously, we demonstrated that a synthesized peptide originating from high mobility group box-1 protein (HMGB1) induces a regenerative cascade through activating endogen...
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Identifiers and source
- Literature Corpus work
- ad413a26-8fa5-5dd4-befc-7d0471575c85
- DOI
- 10.21203/rs.3.rs-892162/v1