Article

Early life tolerance depends on a subset of specialized dendritic cells and is reinforced by the skin microbiota

2022-06-26

Abstract excerpt

<h4>Summary</h4> Early life establishment of tolerance to commensal bacteria at barrier surfaces carries enduring implications for immune health but remains poorly understood. Here we show that this process is controlled by microbial interaction with a specialized subset of antigen presenting cells. More particularly, we identify CD301b + type 2 conventional dendritic cells (DC) as a subset in neonatal skin spec...

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Identifiers and source

Literature Corpus work: ba725006-bb6c-5449-af91-501d870617ae
DOI: 10.1101/2022.06.23.497363

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