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Group 3 innate lymphoid cells (ILC3s): Origin, differentiation, and plasticity in humans and mice

1 Jun 2015

Abstract excerpt

Since their discovery, innate lymphoid cells (ILCs) have been the subject of intense research. As their name implies, ILCs are innate cells of lymphoid origin, and can be grouped into subsets based on their cytotoxic activity, cytokine profile, and the transcriptional requirements during ILC differentiation. The main ILC groups are "killer" ILCs, comprising NK cells, and "helper-like" ILCs (including ILC1s,...

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PMID: 26031799
DOI: 10.1002/eji.201545598

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