Article

Selective vulnerability of supragranular layer neurons in schizophrenia

2020-11-19

Abstract excerpt

<h4>ABSTRACT</h4> Schizophrenia is one of the most wide-spread mental brain disorders with complex and largely unknown etiology. To characterize the impact of schizophrenia at a cellular level, we performed single nucleus RNA sequencing of >190,000 neurons from the dorsolateral prefrontal cortex of patients with schizophrenia and matched controls (7 vs 11, respectively). In addition, to correlate data with cortic...

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Literature Corpus work: 101cafcd-1768-5dfc-a663-9cba8ae1bff4
DOI: 10.1101/2020.11.17.386458

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