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Article

Local Oxygen Tension Dictates Hematopoietic Cell Growth and Potency

2025-09-20

Abstract excerpt

Hematopoietic stem and progenitor cells support a lifetime supply of blood and immune cells, can become neoplastic when dysregulated, and constitute a powerful cell therapy vehicle for hematologic diseases. Here we provide the most comprehensive study of hematopoietic oxygen (O 2 ) dependency to date, demonstrating that human hematopoietic cell numbers, growth, biochemical properties, and functional potency is af...

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Identifiers and source

Literature Corpus work
694375b9-c550-55d1-a0ae-4ec7d5f504b2
DOI
10.1101/2025.09.18.674068
Open publication

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Local Oxygen Tension Dictates Hematopoietic Cell Growth and PotencyDOI 10.1101/2025.09.18.674068
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