Article
Systematic investigation of oxygen and growth factors in clinically valid ex vivo expansion of cord blood CD34(+) hematopoietic progenitor cells.
Cytotherapy - 1 Jul 2012
Tursky Melinda L, Collier Fiona M, Ward Alister C, Kirkland Mark A
Abstract excerpt
BACKGROUND AIMS: Cord blood is considered to be a superior source of hematopoietic stem and progenitor cells for transplantation, but clinical use is limited primarily because of the low numbers of cells harvested. Ex vivo expansion has the potential to provide a safe, effective means of increasing cell numbers. However, an absence of consensus regarding optimum expansion conditions prevents standard...
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