Article

Deciphering of single-cell chromatin accessibility and transcriptome reveals the discrepancy for <i>ex vivo</i> human erythropoiesis

2025-04-16

Abstract excerpt

<h4>Background</h4> Erythroid cells can be generated from hematopoietic stem and progenitor cells (HSPC) derived from various sources; however, few studies decode ex vivo human erythropoiesis for the discrepancies at single-cell multi-omics resolution and uncover the underlying restraints for erythrocyte regeneration. <h4>Results</h4> We deciphered ex vivo human erythropoiesis at two differentiation states fr...

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Literature Corpus work: 4ad5382d-509c-5bc6-a89c-b0b56c7c85eb
DOI: 10.1101/2025.04.15.648947

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