Article

Conformation-based detection of tau seeds with a novel VHH

2025-12-08

Abstract excerpt

<title>Abstract</title> <p>In Alzheimer’s disease (AD) and related tauopathies, progressive pathology has been linked to prion mechanisms whereby ordered tau assemblies, or “seeds,” form in one cell and transit to neighboring or connected cells where they serve as templates for their own replication. While post-translational modifications of pathological tau have been useful to mark pathology, effective methods t...

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Literature Corpus work: 69191d73-4789-5eb1-9898-8182734b177c
DOI: 10.21203/rs.3.rs-8274351/v1

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