Article

Selective Targeting of Pathogenic Tau Seeds via a Novel VHH

2025-01-13

Abstract excerpt

In Alzheimer’s disease (AD) and related tauopathies, progressive pathology has been linked to prion mechanisms, whereby ordered tau assemblies, or “seeds,” form in one cell and transit to neighboring or connected cells where they serve as templates for their own replication. Despite intensive efforts to develop early diagnosis and effective treatment, none has emerged. This is due partly to the structural heteroge...

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Identifiers and source

Literature Corpus work: 7d2edb5d-256e-5687-8596-aea56c68db00
DOI: 10.1101/2025.01.13.632833

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