Article

CD8<sup>+</sup>T-cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

2020-10-05

Abstract excerpt

<h4>ABSTRACT</h4> Indigenous people worldwide are at high-risk of developing severe influenza disease. HLA-A*24:02 allele, highly prevalent in Indigenous populations, is associated with influenza-induced mortality, although the basis for this association is unclear. We defined CD8 + T-cell immune landscapes against influenza A (IAV) and B (IBV) viruses in HLA-A*24:02-expressing Indigenous and non-Indigenous indivi...

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Literature Corpus work: 68bd6a39-0aa3-501c-8430-20854d4011f8
DOI: 10.1101/2020.10.02.20206086

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