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Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians.

Immunology and cell biology - 1 Apr 2016

Clemens E Bridie, Grant Emma J, Wang Zhongfang, Gras Stephanie, Tipping Peta, Rossjohn Jamie, Miller Adrian, Tong Steven Y C, Kedzierska Katherine

Abstract excerpt

Indigenous populations, including Indigenous Australians, are highly susceptible to severe influenza disease and the underlying mechanisms are unknown. We studied immune and genetic factors that could predicate severe influenza disease in Indigenous Australians enrolled in the LIFT study: looking into influenza T-cell immunity. To examine CD8(+) T-cell immunity, we characterised human leukocyte antigen (HLA)...

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Source

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Identifiers

PMID: 26493179
DOI: 10.1038/icb.2015.93
PMCID: PMC4840236

Genes

IFITM3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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