Article

A CRISPR-Nonhomologous End-Joining-based strategy for rapid and efficient gene disruption in <i>Mycobacterium abscessus</i>

2024-01-30

Abstract excerpt

Mycobacterium abscessus , a fast-growing, non-tuberculous mycobacterium resistant to most antimicrobial drugs, causes many types of serious infections in humans, posing a significant public health challenge. Currently, effective genetic manipulation tools for M. abscessus are still being developed, which hampers research and therapeutic development. However, the clustered regularly interspaced short palindromic r...

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Literature Corpus work: 6874a0d2-cc41-5120-98c8-41ab33afb7d4
DOI: 10.1101/2024.01.29.577284

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