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The future of CRISPR in Mycobacterium tuberculosis infection

27 May 2023

Abstract excerpt

Clustered Regularly Interspaced Short Palindromic repeats (CRISPR)-Cas systems rapidly raised from a bacterial genetic curiosity to the most popular tool for genetic modifications which revolutionized the study of microbial physiology. Due to the highly conserved nature of the CRISPR locus in Mycobacterium tuberculosis, the etiological agent of one of the deadliest infectious diseases globally, initially, little...

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PMID: 37245014
DOI: 10.1186/s12929-023-00932-4

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