Article

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

2020-07-24

Abstract excerpt

<h4>Summary</h4> The SARS-CoV-2 Spike protein acquired a D614G mutation early in the COVID-19 pandemic that appears to confer on the virus greater infectivity and is now the globally dominant form of the virus. Certain of the current vaccines entering phase 3 trials are based on the original D614 form of Spike with the goal of eliciting protective neutralizing antibodies. To determine whether D614G mediates neutra...

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Literature Corpus work: 68388840-d7b3-5461-9a9f-70aa24852ea2
DOI: 10.1101/2020.07.22.20159905

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