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Article

Impact of mutations in SARS-COV-2 spike on viral infectivity and antigenicity.

Briefings in bioinformatics - 17 Jan 2022

Zhou Wenyang, Xu Chang, Wang Pingping, Anashkina Anastasia A, Jiang Qinghua

Abstract excerpt

Since the outbreak of SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, the viral genome has acquired numerous mutations with the potential to alter the viral infectivity and antigenicity. Part of mutations in SARS-CoV-2 spike protein has conferred virus the ability to spread more quickly and escape from the immune response caused by the monoclonal neutralizing antibody or vaccination. Herein, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34518867
DOI: 10.1093/bib/bbab375
PMCID: PMC8499914

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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