Article

Physical mechanisms of nanoparticle-membrane interactions: A coarse-grained study

2025-11-02

Abstract excerpt

Nanoparticles (NPs) are promising drug carriers for targeted therapies, diagnostic imaging and advanced vaccines. However, their clinical translation is limited by complex biological barriers that reduce cellular uptake and efficacy. Specifically, the interaction with the cellular membrane controls nanoparticle adhesion, wrapping or full engulfment, which ultimately govern nanoparticle internalization efficiency....

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Literature Corpus work: 68166a2d-31ea-519a-8a7c-4049f3ea0390
DOI: 10.1101/2025.10.31.685850

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