Article

Membrane and glycocalyx tethering of DNA nanostructures for enhanced uptake

2023-03-10

Abstract excerpt

DNA nanostructures (DNs) have been increasingly utilized in biosensing, drug delivery, diagnostics and therapeutics, because of their programmable assembly, control over size and shape, and ease of functionalization. However, the low cellular uptake of DNs has limited their effectiveness in these biomedical applications. Here we demonstrate the potential of membrane and glycocalyx binding as general strategies to...

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Literature Corpus work: 2e333f3f-3961-5fb5-92e6-87318c008fb0
DOI: 10.1101/2023.03.09.529286

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