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Tunable Rigid Spikes on Virus-Like Porous Silica Enable Mechanistically Controlled Nanovaccine Platforms

2026-04-29

Abstract excerpt

Virus-like particles represent an emerging and promising vaccine platform. However, these particles are inherently mechanically soft and have limited control over particle surface architecture, thereby constraining their immunological control. Herein, we report the rational design of bioinspired virus-like porous silica (VLPSi) nanoparticles (NPs) with tunable and mechanically rigid spike architectures that functi...

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Literature Corpus work
da24b483-7fbb-56ab-b15f-1439c3210a9c
DOI
10.64898/2026.04.26.720861
Open publication

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Tunable Rigid Spikes on Virus-Like Porous Silica Enable Mechanistically Controlled Nanovaccine PlatformsDOI 10.64898/2026.04.26.720861
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