Article

Apolipoprotein interaction induces shape remodeling and lipid phase separation in giant unilamellar vesicles

2025-04-16

Abstract excerpt

Apolipoprotein A-I (ApoA-I) – a 243-residue amphipathic protein containing an N-terminal globular domain and a primarily helical C-terminal lipid binding domain – is a principal protein component of high-density lipoprotein (HDL) or “good” cholesterol, which is an essential component of lipid homeostasis in humans. Synthesized in the liver and intestine and excreted in the blood, ApoA-I undergoes complex, cooperat...

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Literature Corpus work: c166fe39-4e10-5148-8ecd-6f4c6c83d709
DOI: 10.1101/2025.04.10.648283

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