Back to search

Article

Functional networks of the human bromodomain-containing proteins

2022-02-22

Abstract excerpt

<h4>Background</h4> Bromodomains are a structurally conserved epigenetic reader domain that bind to acetylated lysine residues in both histone and non-histone proteins. Bromodomain-containing proteins (BRD proteins) function are established scaffolds in the assembly of multi-protein complexes to regulate diverse biological processes. BRD proteins have been classified based on biological and functional similarity,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
67f9ae55-3917-598d-b4ed-f83b8a33de5b
DOI
10.1101/2022.02.21.481364
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Functional networks of the human bromodomain-containing proteinsDOI 10.1101/2022.02.21.481364
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.Semantic proximity
Biological function and histone recognition of family IV bromodomain‐containing proteinsSemantic proximity
Functional Roles of Bromodomain Proteins in CancerSemantic proximity
The bromodomain: a chromatin browser?Semantic proximity
Bromodomain 4: a cellular Swiss army knifeSemantic proximity
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain FamilySemantic proximity
The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsSemantic proximity
Post-Translational Modifications of BRD4: Therapeutic Targets for TumorSemantic proximity
BRD4 in physiology and pathology: ‘‘BET’’ on its partnersSemantic proximity
The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsSemantic proximity
Bromodomain containing 4 (BRD4) as a potential prognostic marker in a pan-cancer analysis of human tumorsSemantic proximity
Bromodomains as therapeutic targets in cancerSemantic proximity
Select a neighboring publication to make it the new centre.