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Article

BRD4 in physiology and pathology: ‘‘BET’’ on its partners

26 Oct 2021

Abstract excerpt

Bromodomain-containing 4 (BRD4), a member of Bromo and Extra-Terminal (BET) family, recognizes acetylated histones and is of importance in transcription, replication, and DNA repair. It also binds non-histone proteins, DNA and RNA, contributing to development, tissue growth, and various physiological processes. Additionally, BRD4 has been implicated in driving diverse diseases, ranging from cancer, viral...

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PMID: 34697817
DOI: 10.1002/bies.202100180

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