Article
The bromodomain: a chromatin browser?
Frontiers in bioscience : a journal and virtual library - 1 Aug 2001
Filetici P, P O, Ballario P
Abstract excerpt
Reversible modification of histone tails is a regulatory step in chromatin remodeling. The N-terminal tails of histones are signaling platforms that carry amino acid residues for post-translational modification and contribute to chromosomal higher order structure. These modifications are performed by a number of chromatin modulators such as histone (h) acetyltransferase, h-deacetylase, h-methyltransferase and...
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