Article

The P681H mutation in the Spike glycoprotein escapes IFITM restriction and is necessary for type I interferon resistance in the SARS-CoV-2 alpha variant

2022-08-15

Abstract excerpt

<h4>ABSTRACT</h4> The appearance of new dominant variants of concern (VOCs) of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) threatens the global response to the COVID-19 pandemic. Of these, the alpha variant (also known as B.1.1.7) that appeared initially in the UK became the dominant variant in much of Europe and North America in the first half of 2021. The Spike (S) glycoprotein of alpha ac...

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Literature Corpus work: 67f10f21-6d7b-59d2-96ca-dd78eeaf8755
DOI: 10.1101/2022.08.11.503706

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