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Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by Human Genomic Variations that Regulate Expression of <i>TMPRSS2</i> and <i>MX1</i> Genes

2020-05-05

Abstract excerpt

COVID-19 pandemic is a major human tragedy. Worldwide, SARS-CoV-2 has already infected over 3 million and has killed about 230,000 people. SARS-CoV-2 originated in China and, within three months, has evolved to an additional 10 subtypes. One particular subtype with a non-silent (Aspartate to Glycine) mutation at 614 th position of the Spike protein (D614G) rapidly outcompeted other pre-existing subtypes, includin...

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Literature Corpus work
6b103ed3-3c01-52aa-9d66-5fdea69536e0
DOI
10.1101/2020.05.04.075911
Open publication

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Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by Human Genomic Variations that Regulate Expression of <i>TMPRSS2</i> and <i>MX1</i> GenesDOI 10.1101/2020.05.04.075911
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